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Jiayu Chen

  • Research Scientist
  • Ph.D, Electrical Engineering, University of New Mexico
  • MS, Electrical Engineering, University of New Mexico
  • BS, Electrical Engineering, Shanghai Jiao Tong University, China
  • jchen @ mrn.org
  • I am mainly interested in multimodal data fusion and data mining. My work has been focused on developing novel methods to analyze complex high-dimensional imaging and genetic data. My current project integrates large-sample SNP and CNV data, as well as sMRI, fMRI and DTI, to understand better how genetic variations regulate the neural basis of schizophrenia and bipolar disorder.

    Methods and citations:

    • pICA-R: semi-blind parallel ICA with reference - Chen J, Calhoun VD, Pearlson GD, Perrone-Bizzozero N, Sui J, Turner JA, et al. (2013) Guided exploration of genomic risk for gray matter abnormalities in schizophrenia using parallel independent component analysis with reference. Neuroimage 83C: 384-396.
    • pICA-MR: parallel ICA with multiple references:
      • Chen J, Calhoun VD, Ulloa AE, Liu J (2014) Parallel ICA with multiple references: a semi-blind multivariate approach. Conf Proc IEEE Eng Med Biol Soc 2014: 6659-62.
      • Chen J, Hutchison KE, Calhoun VD, Claus ED, Turner JA, Sui J, et al. (2015) CREB-BDNF pathway influences alcohol cue-elicited activation in drinkers. Hum Brain Mapp 36: 3007-19.
    • The above mentioned algorithms are integrated in the Fusion ICA Toolbox.